Human CellExp™ FGF-8b, Human Recombinant

Catalog number
6451-50
Name
Human CellExp™ FGF-8b, Human Recombinant
Size
50 μg
Price
849.00 EUR
Supplier

Details

Background
FGF8 is part of the fibroblast growth factor family. FGF family members have wide mitogenic and cell survival activities, and participate in a variety of biological processes, including embryonic development, cell growth, morphogenesis, tissue repair, tumor growth and invasion. FGF8 supports androgen and anchorage independent growth of mammary tumor cells. FGF8 over expression increases tumor growth and angiogensis. The adult expression of FGF-8 gene is restricted to testes and ovaries. FGF8 functions as an embryonic epithelial factor. FGF8 takes part in midbrain and limb development, organogenesis, embryo gastrulation and left-right axis determination.
Concentration
N/A
Molecular weight
30 to 45 kDa, monomer, glycosylated
Synonym
Human Cellexp Human Recombinant FGF-8b
Other name
FGF8B, FGF-8B, FGF8-B, KAL6, HBGF-8, HBGF8, AIGF, HBGF-8, MGC149376, fibroblast growth factor 8.
NCBI gene number
2253
NCBI gene
FGF8
Gene source
Human
NCBI number
P55075
Recombinant
Yes
Source
Human cell expressed
Purification
≥95%
Tested applications
SDS-PAGE, N/A
Level of endotoxin
<1.0 EU per 1 μg of protein
Tested activity
N/A
Biological activity
ED is typically 15 to 60 ng/mL. The specific activity was determined by the dose-dependent stimulation of the proliferation of the Balb / 3T3 cell line.
Reesults
15 to 60 ng/ml
Binding ability
N/A
Unit
N/A
Storage condition
-80°C
Shipping under
gel pack
Physical appearance
Lyophilized
Physical properties
Lyophilized in solution of 10 mM Tris-HCl, pH 7.4, with 800 mM NaCl
How to reconstitute
Reconstitute in sterile water containing 0.1% endotoxin-free recombinant human serum albumin.
Aa sequence
N/A
Before use
Centrifuge the vial prior to opening.
Notes
For Research Use Only! Not to be used in humans
Properties
Human proteins, cDNA and human recombinants are used in human reactive ELISA kits and to produce anti-human mono and polyclonal antibodies. Modern humans (Homo sapiens, primarily ssp. Homo sapiens sapiens). Depending on the epitopes used human ELISA kits can be cross reactive to many other species. Mainly analyzed are human serum, plasma, urine, saliva, human cell culture supernatants and biological samples.
Additional source
Recombinants or rec. proteins
Group
recombinants