CHIR 99021 for cell activation

Catalog number
1677-25
Name
CHIR 99021 for cell activation
Size
25 mg
Price
866.00 EUR
Supplier

Details

Description
A potent and highly selective inhibitor of glycogen synthase kinase-3β (GSK-3β) (IC₅₀ = 6.7 nM). CHIR99021 has been shown to allow for long-term expansion of murine embryonic stem cells in a chemically-defined medium in conjunction with MEK/MAPK inhibitor PD184352 and fibroblast growth factor receptor (FGFR) inhibitor SU5402.
Peptide sequence
N/A
CAS number
252917-06-9
Molecular weight
465.34
Category
Biochemicals
Other name
6-((2-((4-(2,4-Dichlorophenyl)-5-(4-methyl-1H-imidazol-2-yl)pyrimidin-2-yl)amino)ethyl)amino)nicotinonitrile; CT99021
Molecular formula
C₂₂H₁₈Cl₂N₈
Physical appearance
Off-white solid
Supplied with
N/A
Is this a salt?
No
Is it cell-permeable?
Yes
Purification
≥98% by HPLC
Reconstitute instructions
DMSO ( 100 mM)
Storage condition
-20°C
Shipping condition
RT
Maximum time for storage
24 months
Storage instructions
Protect from air and moisture
Tissue
cell
Additional description
For cells, cell lines and tissues in culture till half confluency.