Human CellExp™ TGF-beta 2, Human Recombinant

Catalog number
6480-50
Name
Human CellExp™ TGF-beta 2, Human Recombinant
Size
50 µg
Price
2568.00 EUR
Supplier

Details

Background
Transforming growth factor betas (TGFβ) mediate many cell-cell interactions that occur during embryonic development. Three TGFβs have been identified in mammals. TGF Beta 1, TGF Beta 2 and TGF Beta 3 are each synthesized as precursor proteins that are very similar in that each is cleaved to yield a 112 amino acid polypeptide that remains associated with the latent portion of the molecule. TGF-beta 1 is involved in hematopoiesis and endothelial differentiation.
Concentration
N/A
Molecular weight
25 kDa, homodimer, nonglycosylated
Synonym
Human Cellexp Human Recombinant TGF-beta 2
Other name
Transforming growth factor, beta 2, cetermin, Glioblastoma-derived T-cell suppressor factor, polyergin, G-TSF, TGF-beta2, TGF-beta-2, transforming growth factor beta-2, BSC-1 cell growth inhibitor, TGFB-2.
NCBI gene number
7042
NCBI gene
TGFB2
Gene source
Human
NCBI number
P61812
Recombinant
Yes
Source
Human 293 cell expressed
Purification
> 95%
Tested applications
SDS-PAGE, N/A
Level of endotoxin
<1.0 EU per 1 μg of protein
Tested activity
N/A
Biological activity
ED₅₀ is typically 0.1 to 0.5 ng/mL. The specific activity was determined by the dose-dependent inhibition of IL-4 induced proliferation of mouse HT-2 cells (BALB/c spleen activated by sheep erythrocytes in the presence of IL-2).
Reesults
0.1 to 0.5 ng/ml
Binding ability
N/A
Unit
N/A
Storage condition
-80°C
Shipping under
gel pack
Physical appearance
Lyophilized
Physical properties
Lyophilized from 50 mM sodium acetate, pH 4.5 and 350 mM NaCl.
How to reconstitute
Reconstitute in sterile 4 mM HCl containing 0.1% endotoxin-free recombinant human serum albumin.
Aa sequence
N/A
Before use
Centrifuge the vial prior to opening.
Notes
For Research Use Only! Not to be used in humans
Properties
Human proteins, cDNA and human recombinants are used in human reactive ELISA kits and to produce anti-human mono and polyclonal antibodies. Modern humans (Homo sapiens, primarily ssp. Homo sapiens sapiens). Depending on the epitopes used human ELISA kits can be cross reactive to many other species. Mainly analyzed are human serum, plasma, urine, saliva, human cell culture supernatants and biological samples.
Additional source
Recombinants or rec. proteins
Group
recombinants