Vandetanib for cell activation

Catalog number
1751-100
Name
Vandetanib for cell activation
Size
100 mg
Price
376.00 EUR
Supplier

Details

Description
A potent inhibitor of kinase insert domain-containing receptor [KDR/vascular endothelial growth factor receptor (VEGFR) 2] tyrosine kinase activity (IC₅₀ = 40 nM). This compound also inhibits fms-like tyrosine kinase 4 (VEGFR3, IC₅₀ = 110 nM) and epidermal growth factor receptor (EGFR/HER1, IC₅₀ = 500 nM) but shows selectivity relating to a range of other tyrosine and serine-threonine kinases.
Peptide sequence
N/A
CAS number
443913-73-3
Molecular weight
475.35
Category
Biochemicals
Other name
N-(4-Bromo-2-fluorophenyl)-6-methoxy-7-((1-methylpiperidin-4-yl)methoxy)quinazolin-4-amine; ZD6474, Zactima
Molecular formula
C₂₂H₂₄BrFN₄O₂
Physical appearance
White solid
Supplied with
N/A
Is this a salt?
No
Is it cell-permeable?
Yes
Purification
≥98% by HPLC
Reconstitute instructions
DMSO (30 mg/ml) or EtOH (10 mg/ml)
Storage condition
-20°C
Shipping condition
gel pack
Maximum time for storage
24 months
Storage instructions
Protect from air and moisture
Tissue
cell
Additional description
For cells, cell lines and tissues in culture till half confluency.