H-89 Dihydrochloride for cell activation

Catalog number
1768-5
Name
H-89 Dihydrochloride for cell activation
Size
5 mg
Price
452.00 EUR
Supplier

Details

Description
A cell-permeable, ATP-competitive inhibitor of Protein Kinase A (PKA) (IC₅₀ = 50 nM). Also inhibits other kinases, including MSK1 , S6K1 and ROCKII with IC₅₀ values of 120 nM, 80 nM and 270 nM respectively.
Peptide sequence
N/A
CAS number
127243-85-0
Molecular weight
519.28
Category
Biochemicals
Other name
N-[2-[[3-(4-Bromophenyl)-2-propen-1-yl]amino]ethyl]-5-Isoquinolinesulfonamide dihydrochloride
Molecular formula
C₂₀H₂₀BrN₃O₂S.2HCl
Physical appearance
White to off-white solid
Supplied with
N/A
Is this a salt?
No
Is it cell-permeable?
Yes
Purification
≥98% by HPLC
Reconstitute instructions
DMSO (200 mg/ml) and H₂O (25 mg/ml)
Storage condition
-20°C
Shipping condition
gel pack
Maximum time for storage
24 months
Storage instructions
Protect from air and light
Tissue
cell
Additional description
For cells, cell lines and tissues in culture till half confluency.