PI3-Kɣ Inhibitor, AS-605240 for cell activation

Catalog number
1780-5
Name
PI3-Kɣ Inhibitor, AS-605240 for cell activation
Size
5 mg
Price
344.00 EUR
Supplier

Details

Description
Cell-permeable. A potent and selective inhibitor of PI 3-kinase γ (PI3Kγ) (IC₅₀ = 8 nM). Displays>33-fold selectivity over PI3Kδ and PI3Kβ and 7.5-fold selectivity over PI3Kα.
Peptide sequence
N/A
CAS number
648450-29-7
Molecular weight
257.27
Category
Biochemicals
Other name
5-(6-Quinoxalinylmethylene)-2,4-thiazolidine-2,4-dione
Molecular formula
C₁₂H₇N₃O₂S
Physical appearance
Pink to reddish solid
Supplied with
N/A
Is this a salt?
No
Is it cell-permeable?
Yes
Purification
≥98% by HPLC
Reconstitute instructions
DMSO ( 1 mM)
Storage condition
-20°C
Shipping condition
gel pack
Maximum time for storage
48 months
Storage instructions
Protect from air and light
Tissue
cell
Additional description
For cells, cell lines and tissues in culture till half confluency.Tissue, pathway, proteinase, peptidase, protease ,acrosin, lipoprotein, activator, caspase, trypsin, papain, esterase inhibitors are proteins or receptor ligands or receptor antagonists that bind to an enzyme receptor and decreases its activity. Since blocking an enzyme's activity can kill a pathogen or correct a metabolic imbalance, many drugs are enzyme inhibitors. Not all receptor antagonist that bind to enzymes are inhibitors; enzyme activator ligands or agonists bind to enzymes and increase their enzymatic activity, while enzyme substrates bind and are converted to products in the normal catalytic cycle of the enzyme.