sFas Receptor, human recombinant

Catalog number
7141-50
Name
sFas Receptor, human recombinant
Size
50 μg
Price
895.00 EUR
Supplier

Details

Synonyms
soluble Fas receptor (sFasR), TNFRSF6, CD95, Apo I, Fas Antigen
Alternates names
soluble Fas receptor (sFasR), TNFRSF6, CD95, Apo I, Fas Antigen
Taglines
Leads to down-regulation of the immune response
Biomolecule/Target
sFas Receptor
NCBI Gene ID #.
355
NCBI Gene Symbol
FASL
Gene Source
Human
Accession #
P25445
Recombinant
Yes
Source
E. coli.
Purity
N/A
Endotoxin Level
<0.1 ng/μg of protein (
Activity (Specifications/test method)
ED50 was determined by its ability to inhibit the cytotoxicity of Jurkat cells using a concentration range of 10-15 μg/ml in the presence of 2ng/ml of hFasL.
Biological activity
ED50 was determined by its ability to inhibit the cytotoxicity of Jurkat cells using a concentration range of 10-15 μg/ml in the presence of 2ng/ml of hFasL.
Results
N/A
Molecular Weight
17.6 kDa
Storage Temp.
-20°C
Shipping
Gel Pack
Shelf Life
1 year
Concentration
N/A
Appearance
Lyophilized powder
Physical form description
Sterile filtered through a 0.2 micron filter. Lyophilized with no additives.
Reconstitution Instructions
Centrifuge the vial prior to opening. Reconstitute in water to a concentration of 0.1-1.0 mg/ml. Do not vortex. This solution can be stored at 2-8°C for up to 1 week. For extended storage, it is recommended to further dilute in a buffer containing a carrier protein (example 0.1% BSA) and store in working aliquots at -20°C to -80°C.
Handling
Centrifuge the vial prior to opening.
Usage
For Research Use Only! Not to be used in humans
Properties
Human proteins, cDNA and human recombinants are used in human reactive ELISA kits and to produce anti-human mono and polyclonal antibodies. Modern humans (Homo sapiens, primarily ssp. Homo sapiens sapiens). Depending on the epitopes used human ELISA kits can be cross reactive to many other species. Mainly analyzed are human serum, plasma, urine, saliva, human cell culture supernatants and biological samples.
Description
The receptors are ligand binding factors of type 1, 2 or 3 and protein-molecules that receive chemical-signals from outside a cell. When such chemical-signals couple or bind to a receptor, they cause some form of cellular/tissue-response, e.g. a change in the electrical-activity of a cell. In this sense, am olfactory receptor is a protein-molecule that recognizes and responds to endogenous-chemical signals, chemokinesor cytokines e.g. an acetylcholine-receptor recognizes and responds to its endogenous-ligand, acetylcholine. However, sometimes in pharmacology, the term is also used to include other proteins that are drug-targets, such as enzymes, transporters and ion-channels.
Additional source
Recombinants or rec. proteins
Group
recombinants