BMP-11/GDF-11, human recombinant

Catalog number
7155-50
Name
BMP-11/GDF-11, human recombinant
Size
50 μg
Price
895.00 EUR
Supplier

Details

Synonyms
Growth/Differentiation Factor-11, BMP-11
Alternates names
Growth/Differentiation Factor-11, BMP-11
Taglines
Suppresses neurogenesis through a myostatin-like pathway
Biomolecule/Target
BMP-11
NCBI Gene ID #.
10220
NCBI Gene Symbol
GDF11
Gene Source
Human
Accession #
O95390
Recombinant
Yes
Source
E. coli.
Purity
N/A
Endotoxin Level
<0.1 ng/μg of protein (
Activity (Specifications/test method)
Determined by its ability to inhibit induced alkaline phosphatase production by ATDC-5 chondrogenic cells. The ED50 for this effect is 0.08-0.10 μg/ml.
Biological activity
Determined by its ability to inhibit induced alkaline phosphatase production by ATDC-5 chondrogenic cells. The ED50 for this effect is 0.08-0.10 μg/ml.
Results
N/A
Molecular Weight
25 kDa
Storage Temp.
-20°C
Shipping
Gel Pack
Shelf Life
1 year
Concentration
N/A
Appearance
Lyophilized powder
Physical form description
Sterile filtered through a 0.2 micron filter. Lyophilized with no additives.
Reconstitution Instructions
Centrifuge the vial prior to opening. Reconstitute in water to a concentration of 0.1-1.0 mg/ml. Keep pH below 5.0. Do not vortex. This solution can be stored at 2-8°C for up to 1 week. For extended storage, it is recommended to further dilute in a buffer containing a carrier protein (example 0.1% BSA) and store in working aliquots at -20°C to -80°C.
Handling
Centrifuge the vial prior to opening.
Usage
For Research Use Only! Not to be used in humans
Properties
Human proteins, cDNA and human recombinants are used in human reactive ELISA kits and to produce anti-human mono and polyclonal antibodies. Modern humans (Homo sapiens, primarily ssp. Homo sapiens sapiens). Depending on the epitopes used human ELISA kits can be cross reactive to many other species. Mainly analyzed are human serum, plasma, urine, saliva, human cell culture supernatants and biological samples.
Additional source
Recombinants or rec. proteins
Group
recombinants