CP-31398 Dihydrochloride for cell activation

Catalog number
1815-25
Name
CP-31398 Dihydrochloride for cell activation
Size
25 mg
Price
447.00 EUR
Supplier

Details

Description
A styrylquinazoline derivative that acts as a p53 stabilizing agent. It not only restores p53 functions in mutant p53-expressing cells but can also significantly increase the protein level and promote the activity of wild-type p53 in multiple human cancer cell lines, leading to cell cycle arrest or apoptosis. CP-31398 enhances the protein levels of wild-type p53 by blockade of ubiquitination and degradation of p53 without interrupting the physical association between p53 and MDM2 in vivo.
Peptide sequence
N/A
CAS number
1217195-61-3
Molecular weight
435.39
Category
Biochemicals
Other name
N'-[2-[2-(4-Methoxyphenyl)ethenyl]-4-quinazolinyl]-N,N-dimethyl-1,3-propanediamine Dihydrochloride
Molecular formula
C₂₂H₂₆N₄O.2HCl
Physical appearance
Yellow solid
Supplied with
N/A
Is this a salt?
No
Is it cell-permeable?
Yes
Purification
≥98% by TLC
Reconstitute instructions
H₂O (25 mg/ml) or DMSO (5 mg/ml)
Storage condition
-20°C
Shipping condition
gel pack
Maximum time for storage
24 months
Storage instructions
Protect from light and moisture
Tissue
cell
Additional description
For cells, cell lines and tissues in culture till half confluency.