SU 1498 for cell activation

Catalog number
1836-5
Name
SU 1498 for cell activation
Size
5 mg
Price
251.00 EUR
Supplier

Details

Description
A potent and selective inhibitor (IC₅₀ = 700 nM) of vascular endothelial growth factor receptor 2 (VEGFR 2) (also known as Flk1). Very weak inhibitor of PDGFR-kinase (IC₅₀>50 µM), EGFR-kinase (IC₅₀>100 µM)and HER-2 kinase (IC₅₀>100 µM). SU1498 has been shown to cause accumulation of phosphorylated ERK and inhibits its activity in vivo and in vitro by inhibition of ERK dephosphorylation.
Peptide sequence
N/A
CAS number
N/A
Molecular weight
390.52
Category
Biochemicals
Other name
Tyrphostin SU 1498; (E)-N-(3″-Phenylpropyl)-α-cyano-3′,5′-diisopropyl-4′-hydroxycinnamamide
Molecular formula
C₂₅H₃₀N₂O₂
Physical appearance
Yellow powder
Supplied with
N/A
Is this a salt?
No
Is it cell-permeable?
Yes
Purification
≥98% by TLC
Reconstitute instructions
DMSO (~20 mg/ml)
Storage condition
-20°C
Shipping condition
gel pack
Maximum time for storage
24 months
Storage instructions
Protect from air and light
Tissue
cell
Additional description
For cells, cell lines and tissues in culture till half confluency.