Persephin, human recombinant

Catalog number
7185-50
Name
Persephin, human recombinant
Size
50 μg
Price
725.00 EUR
Supplier

Details

Synonyms
PSP, PSPN
Alternates names
PSP, PSPN
Taglines
Promotes the survival of ventral midbrain dompaminergic neurons and motor neurons
Biomolecule/Target
Persephin
NCBI Gene ID #.
5623
NCBI Gene Symbol
PSPN
Gene Source
Human
Accession #
O60542
Recombinant
Yes
Source
E. Coli
Purity
N/A
Endotoxin Level
<0.1 ng/μg of protein (
Activity (Specifications/test method)
Human Persephin induces RET phosphorylation using a concentration range of 0.1-1.0 ng/ml. Human Persephin binds to mammalian GFRα4 with the Kd of 100pM. Other members of the GDNF family (Artemin, GDNF and Neurturin) do not bind to mammalian GFRα4.
Biological activity
Human Persephin induces RET phosphorylation using a concentration range of 0.1-1.0 ng/ml. Human Persephin binds to mammalian GFRα4 with the Kd of 100pM. Other members of the GDNF family (Artemin, GDNF and Neurturin) do not bind to mammalian GFRα4.
Results
N/A
Molecular Weight
10.4 kDa
Storage Temp.
-20°C
Shipping
Gel Pack
Shelf Life
1 year
Concentration
N/A
Appearance
Lyophilized powder
Physical form description
Sterile filtered through a 0.2 micron filter. Lyophilized from 0.3 x PBS, pH 7.2
Reconstitution Instructions
Centrifuge the vial prior to opening. Reconstitute in 5 mM Sodium Phosphate, pH 7.5 to a concentration of ≤ 0.5 mg/ml. Do not vortex. This solution can be stored at 2-8°C for up to 1 week. For extended storage, it is recommended to further dilute in a buffer containing a carrier protein (example 0.1% BSA) and store in working aliquots at -20°C to -80°C.
Handling
Centrifuge the vial prior to opening.
Usage
For Research Use Only! Not to be used in humans
Properties
Human proteins, cDNA and human recombinants are used in human reactive ELISA kits and to produce anti-human mono and polyclonal antibodies. Modern humans (Homo sapiens, primarily ssp. Homo sapiens sapiens). Depending on the epitopes used human ELISA kits can be cross reactive to many other species. Mainly analyzed are human serum, plasma, urine, saliva, human cell culture supernatants and biological samples.
Additional source
Recombinants or rec. proteins
Group
recombinants