Curcumin, Curcuma longa (High Purity) for cell activation

Catalog number
1850-50
Name
Curcumin, Curcuma longa (High Purity) for cell activation
Size
50 mg
Price
251.00 EUR
Supplier

Details

Description
Cell-permeable. An antioxidant and dual inhibitor of 5-lipoxygenase (IC₅₀ = 8 µM) and cyclooxygenase (COX) (IC₅₀ = 52 µM). Also inhibits glutathione S-transferase, induction of nitric oxide (NO) in activated macrophages and inhibits EGF-induced tyrosine phosphorylation of EGF receptors. Also shown to be a p300/CREB-binding protein-specific inhibitor of histone acetyltransferase, inhibiting the acetylation of histones H3 and H4 with an IC₅₀ of ~25 µM. Does not affect p300/CREB binding protein-associated factor (PCAF).
Peptide sequence
N/A
CAS number
458-37-7
Molecular weight
368.38
Category
Biochemicals
Other name
1,7-bis(4-Hydroxy-3-methoxyphenyl)-1,6-heptadiene-3,5-dione, Diferuloylmethane
Molecular formula
C₂₁H₂₀O₆
Physical appearance
Orange-yellow solid
Supplied with
N/A
Is this a salt?
No
Is it cell-permeable?
Yes
Purification
≥98%
Reconstitute instructions
DMSO (25 mg/ml) or EtOH (10 mg/ml)
Storage condition
-20°C
Shipping condition
gel pack
Maximum time for storage
24 months
Storage instructions
Protect from air and light
Tissue
cell
Additional description
For cells, cell lines and tissues in culture till half confluency.