PS48 for cell activation
Catalog number
1869-25
Name
PS48 for cell activation
Size
25 mg
Price
349.00 EUR
Supplier
Details
Description
An allosteric phosphoinositide-dependent protein kinase-1 (PDK1) activator (Kd = 10.3 μM). Binds exclusively to the PIF-binding pocket of PDK1, distinct from the ATP binding site. It has recently been found that a combination of PS48, sodium butyrate (Cat. No. 1609-1000), a histone deacetylase inhibitor and the gene Oct-4, could enhance the reprogramming efficiency of keratinocytes isolated from human skin or hair follicles over 25-fold.
Peptide sequence
N/A
CAS number
1180676-32-7
Molecular weight
286.75
Category
Biochemicals
Other name
(2Z)-5-(4-Chlorophenyl)-3-phenyl-2-pentenoic acid
Molecular formula
C₁₇H₁₅ClO₂
Physical appearance
White to off-white solid
Supplied with
N/A
Is this a salt?
No
Is it cell-permeable?
Yes
Purification
≥95% by HPLC
Reconstitute instructions
DMSO (100 mM) or EtOH (50 mM)
Storage condition
-20°C
Shipping condition
gel pack
Maximum time for storage
24 months
Storage instructions
Protect from air and light
Tissue
cell
Additional description
For cells, cell lines and tissues in culture till half confluency.