Deferoxamine Mesylate for cell activation

An iron chelator used for the treatment of acute iron intoxication and of chronic iron overload due to transfusion-dependent anemias. Has been shown to have anti-proliferative effects on vascular smooth muscle cells in vitro and in vivo and to arrest cells in the G1 phase. Induces apoptosis in HL-60 cells by chelating iron. In addition, it has been shown to have antioxidant properties and to protect cells against H₂O₂-induced damage.

N/A

138-14-7

656.79

Biochemicals

DFOM, Deferoxamine methanesulfonate salt, Desferrioxamine mesylate salt

C₂₅H₄₈N₆O₈·CH₄O₃S

White to off-white solid

N/A

No

No

≥98% by HPLC

H₂O (~ 50 mg/ml)

-20°C

gel pack

36 months

Protect from air and moisture

cell

For cells, cell lines and tissues in culture till half confluency.