TG003 for cell activation

Catalog number
1905-25
Name
TG003 for cell activation
Size
25 mg
Price
469.00 EUR
Supplier

Details

Description
Cell-permeable. A potent, specific, reversible, and ATP-competitive inhibitor of Cdc2-like kinase (Clk) (Ki = 10 nM for mClk1/Sty; IC₅₀ = 20 nM, 200 nM,>10 µM, and 15 nM for mClk1, mClk2, mClk3, and mClk4, respectively). Recently, it has been shown that TG003 promotes the skipping of exon 31 in the endogenous dystrophin gene in a dose-dependent manner and increases the production of the dystrophin protein.
Peptide sequence
N/A
CAS number
300801-52-9
Molecular weight
249.33
Category
Biochemicals
Other name
(Z)-1-(3-Ethyl-5-methoxy-2,3-dihydrobenzothiazol-2-ylidene)propan-2-one
Molecular formula
C₁₃H₁₅NO₂S
Physical appearance
Pale yellow solid
Supplied with
N/A
Is this a salt?
No
Is it cell-permeable?
Yes
Purification
≥98% by TLC
Reconstitute instructions
DMSO (>30 mg/ml)
Storage condition
-20°C
Shipping condition
gel pack
Maximum time for storage
36 months
Storage instructions
Protect from air and light
Tissue
cell
Additional description
For cells, cell lines and tissues in culture till half confluency.