GYY 4137 for cell activation

Catalog number
1908-5
Name
GYY 4137 for cell activation
Size
5 mg
Price
121.00 EUR
Supplier

Details

Description
A slow-releasing, water-soluble hydrogen sulfide (H₂S) donor. Displays vasodilator and antihypertensive activity in rats in both acute (L-NAME-induced) or chronic (spontaneously hypertensive) hypertension models. Inhibits LPS-induced release of various proinflammatory mediators (such as IL-1β, IL-6, TNF-α, nitric oxide (NO) and PGE2) in RAW264.7 cells. Increases the synthesis of the anti-inflammatory chemokine IL-10 through NF-κB, ATF-2 and HSP27 dependent pathways in RAW264.7 cells.
Peptide sequence
N/A
CAS number
106740-09-4
Molecular weight
376.47
Category
Biochemicals
Other name
p-​Methoxyphenyl)morpholino-​phosphinodithioic acid
Molecular formula
C₁₁H₁₅NO₂PS₂ · C₄H₁₀NO
Physical appearance
White solid
Supplied with
N/A
Is this a salt?
No
Is it cell-permeable?
Yes
Purification
≥95% by HPLC
Reconstitute instructions
DMSO (15 mg/ml) or water (30 mg/ml)
Storage condition
-20°C
Shipping condition
gel pack
Maximum time for storage
36 months
Storage instructions
Protect from air and moisture
Tissue
cell
Additional description
For cells, cell lines and tissues in culture till half confluency.