Cyclopamine-KAAD for cell activation

Catalog number
1910-50
Name
Cyclopamine-KAAD for cell activation
Size
50 µg
Price
186.00 EUR
Supplier

Details

Description
Cell-permeable. A synthetic derivative of the natural product Cyclopamine (Cat. No. 1578-5) that acts as a specific inhibitor of Smoothened (Smo) and Sonic hedgehog (Shh) intracellular signaling (IC₅₀ = 20 nM in the Shh-LIGHT2 assay).
Peptide sequence
N/A
CAS number
306387-90-6
Molecular weight
697.99
Category
Biochemicals
Other name
3-Keto-N-(aminoethyl-N’-aminocaproyldihydrocinnamoyl)cyclopamine; KAAD-cyclopamine
Molecular formula
C₄₄H₆₃N₃O₄
Physical appearance
Pale yellow solid
Supplied with
N/A
Is this a salt?
No
Is it cell-permeable?
Yes
Purification
≥80% by HPLC
Reconstitute instructions
DMSO or EtOH
Storage condition
-20°C
Shipping condition
gel pack
Maximum time for storage
36 months
Storage instructions
Protect from air and moisture
Tissue
cell
Additional description
For cells, cell lines and tissues in culture till half confluency.