TAK 165 for cell activation

Catalog number
1951-25
Name
TAK 165 for cell activation
Size
25 mg
Price
436.00 EUR
Supplier

Details

Description
Cell-permeable. A potent inhibitor of the human epidermal growth factor receptor 2 (HER2) tyrosine kinase (IC₅₀ = 6 nM). Displays> 4000-fold selectivity over EGFR, FGFR, PDGFR, JAK1 and Src. TAK 165 inhibits bladder, kidney and androgen-independent prostate cancer in vitro and in vivo.
Peptide sequence
N/A
CAS number
366017-09-6
Molecular weight
468.47
Category
Biochemicals
Other name
(E)-4-((4-)1H-1,2,3-Triazol-1-yl)butyl)phenoxy)methyl)-2-(4-trifluoromethyl)oxazole; Mubritinib
Molecular formula
C₂₅H₂₃F₃N₄O₂
Physical appearance
White to off-white solid
Supplied with
N/A
Is this a salt?
No
Is it cell-permeable?
Yes
Purification
≥98% by HPLC
Reconstitute instructions
DMSO (~25 mg/ml) or EtOH (~ 1.7 mg/ml)
Storage condition
-20°C
Shipping condition
gel pack
Maximum time for storage
48 months
Storage instructions
Protect from light and air
Tissue
cell
Additional description
For cells, cell lines and tissues in culture till half confluency.