Emetine dihydrochloride for cell activation

Catalog number
1970-250
Name
Emetine dihydrochloride for cell activation
Size
250 mg
Price
349.00 EUR
Supplier

Details

Description
A bitter-tasting crystalline alkaloid,derived from ipecac root and used in the treatment of amebiasis and as an emetic.Irreversibly blocks protein synthesis by inhibiting the movement of ribosome along the mRNA. Induces hypotension by blocking adrenoreceptors. Inhibits DNA replication in the early S phase. Inhibits HIF-1 activation by hypoxia. Induces apoptosis in leukemia cells. Also, selectively inhibits multiple glioblastoma (GBM) stem cells-enriched cultures.
Peptide sequence
N/A
CAS number
316-42-7
Molecular weight
553.56
Category
Biochemicals
Other name
2S,3R,11bS)-2-{[(1R)-6,7-Dimethoxy-1,2,3,4-tetrahydroisoquinolin-1-yl]methyl}-3-ethyl-9,10-dimethoxy-2,3,4,6,7,11b-hexahydro-1H-pyrido[2,1-a]isoquinoline
Molecular formula
C₂₉H₄₀N₂O₄·2HCl
Physical appearance
White to off-white solid
Supplied with
N/A
Is this a salt?
No
Is it cell-permeable?
No
Purification
≥98% by titration
Reconstitute instructions
Water (~ 100 mg/ml)
Storage condition
+4°C
Shipping condition
gel pack
Maximum time for storage
48 months
Storage instructions
Protect from light and moisture
Tissue
cell
Additional description
For cells, cell lines and tissues in culture till half confluency.