ML130 for cell activation

Catalog number
1974-25
Name
ML130 for cell activation
Size
25 mg
Price
436.00 EUR
Supplier

Details

Description
Cell-permeable. A selective NOD1 (nucleotide-binding oligomerization domain 1) inhibitor. Selectively inhibits NOD1-dependent activation of NF-kB in HEK293 cells (IC₅₀ = 0.56±0.04 µM). Displays high selectivity (>36-fold) over MDP-stimulated signaling in reporter cell lines containing both endogenous and overexpressed NOD2 proteins or TNF-⍺-induced NF-kB activation.
Peptide sequence
N/A
CAS number
799264-47-4
Molecular weight
287.34
Category
Biochemicals
Other name
1-Tosyl-1H-benzo[d]imidazol-2-amine; Nodinitib-1
Molecular formula
C₁₄H₁₃N₃O₂S
Physical appearance
White solid
Supplied with
N/A
Is this a salt?
No
Is it cell-permeable?
Yes
Purification
≥97% by HPLC
Reconstitute instructions
DMSO
Storage condition
-20°C
Shipping condition
gel pack
Maximum time for storage
48 months
Storage instructions
Protect from light and air
Tissue
cell
Additional description
For cells, cell lines and tissues in culture till half confluency.