Human CellExp™ CD306 / LAIR2, human recombinant

Catalog number
7377-50
Name
Human CellExp™ CD306 / LAIR2, human recombinant
Size
50 μg
Price
697.00 EUR
Supplier

Details

Target
CD306/LAIR2
Background
Leukocyte-associated immunoglobulin-like receptor 2 (LAIR2) is also known as CD antigen CD306. LAIR2 contains one Ig-like C2-type (immunoglobulin-like) domain. LAIR2 is a member of the immunoglobulin superfamily and was identified by its similarity to LAIR1, an inhibitory receptor present on mononuclear leukocytes. LAIR2 / CD306 is thought to be secreted and may help modulate mucosal tolerance.
Concentration
N/A
Molecular weight
This protein is fused with 6×His tag at the C-terminus, has a calculated MW of 14.9 kDa. The predicted N-terminus is Gln 22. DTT-reduced Protein migrates as 19-23 kDa.
Synonym
LAIR2, CD306
Other name
LAIR2, CD306
NCBI gene number
3904
NCBI gene
LAIR2
Gene source
Human
NCBI number
Q6ISS4
Recombinant
Yes
Source
HEK293 cells
Purification
≥95%
Tested applications
SDS-PAGE, N/A
Tested activity
N/A
Biological activity
Measured by the ability of the immobilized protein to support the adhesion of HT-29 human colon adenocarcinoma cells. When 10000 cells/well are added to rhLAIR2 /CD306 coated plates (50 μg/ml with 100 μl/well), approximately >40% cells will adhere after 10 minutes at 37°C
Reesults
Measured by the ability of the immobilized protein to support the adhesion of HT-29 human colon adenocarcinoma cells. When 10000 cells/well are added to rhLAIR2 /CD306 coated plates (50 μg/ml with 100 μl/well), approximately >40% cells will adhere after 10 minutes at 37°C
Binding ability
N/A
Unit
N/A
Storage condition
-20°C
Shipping under
Gel Pack
Physical appearance
Lyophilized
Physical properties
Lyophilized from 0.22 μm filtered solution in PBS, pH7.4. Generally 5-8% Mannitol or trehalose is added as a protectant before lyophilization.
How to reconstitute
Centrifuge the vial prior to opening. Reconstitute in sterile PBS, pH 7.4 to a concentration of 50 µg/ml. Do not vortex. This solution can be stored at 2-8°C for up to 1 month. For extended storage, it is recommended to store at -20°C.
Aa sequence
N/A
Before use
Centrifuge the vial prior to opening.
Notes
For Research Use Only! Not to be used in humans
Properties
Human proteins, cDNA and human recombinants are used in human reactive ELISA kits and to produce anti-human mono and polyclonal antibodies. Modern humans (Homo sapiens, primarily ssp. Homo sapiens sapiens). Depending on the epitopes used human ELISA kits can be cross reactive to many other species. Mainly analyzed are human serum, plasma, urine, saliva, human cell culture supernatants and biological samples.
Additional source
Recombinants or rec. proteins
Group
recombinants