Motesanib for cell activation

Catalog number
2022-5
Name
Motesanib for cell activation
Size
5 mg
Price
159.00 EUR
Supplier

Details

Description
Cell-permeable. Motesanib, also known as AMG-706, is a multikinase inhibitor that selectively targets VEGF receptors, platelet-derived growth factor receptors (PDGFRs), and Kit receptors with IC₅₀ values of 2 nM (VEGFR1), 3 nM (VEGFR2), 6 nM (VEGFR3), 84 nM (PDGFR), and 8 nM (Kit). It also potently inhibits angiogenesis and induces regression in tumor xenografts.
Peptide sequence
N/A
CAS number
453562-69-1
Molecular weight
373.45
Category
Biochemicals
Other name
AMG-706
Molecular formula
C₂₂H₂₃N₅O
Physical appearance
White solid
Supplied with
N/A
Is this a salt?
No
Is it cell-permeable?
Yes
Purification
≥98% by HPLC
Reconstitute instructions
DMSO (200 mg/ml) or EtOH (40 mg/ml)
Storage condition
-20°C
Shipping condition
gel pack
Maximum time for storage
24 months
Storage instructions
Protect from air and moisture
Tissue
cell
Additional description
For cells, cell lines and tissues in culture till half confluency.