YM201636 for cell activation

Catalog number
2045-1
Name
YM201636 for cell activation
Size
1 mg
Price
126.00 EUR
Supplier

Details

Description
Cell-permeable. YM-201636 is a selective inhibitor of phosphoinositide kinase (PIK) PIKfyve (IC50 = 33 nM). It inhibits p110α at higher concentration (IC50 = 3 µM). It reversibly impairs endosomal trafficking in NIH3T3 cells, mimicking the effect produced by depleting PIKfyve with siRNA.YM-201636 also blocks retroviral exit by budding from cells.
Peptide sequence
N/A
CAS number
371942-69-7
Molecular weight
467.49
Category
Biochemicals
Other name
6-Amino-N-(3-(4-(4-morpholinyl)pyrido[3′2′:4,5]furo[3,2-d]pyrimidin-2-yl)phenyl)-3-pyridine carboxamide
Molecular formula
C₂₅H₂₁N₇O₃
Physical appearance
White to off-white solid
Supplied with
N/A
Is this a salt?
No
Is it cell-permeable?
Yes
Purification
≥98% by NMR
Reconstitute instructions
DMSO or EtOH
Storage condition
-20°C
Shipping condition
gel pack
Maximum time for storage
24 months
Storage instructions
Protect from air and light
Tissue
cell
Additional description
For cells, cell lines and tissues in culture till half confluency.