YC-1 for cell activation

Catalog number
2061-25
Name
YC-1 for cell activation
Size
25 mg
Price
425.00 EUR
Supplier

Details

Description
Cell-permeable. A nitric oxide (NO) independent, superoxide-sensitive soluble guanylyl cyclase (sGC) activator (EC₅₀ = 18 µM). Induces concentration-dependent increase in cGMP levels in cultured cells and in rabbit aortic rings. Inhibits platelet adhesion to collagen. A non-specific phosphodiesterase (PDE) inhibitor. YC-1 also inhibits HIF-α activity in tumors resulting in blocked angiogenesis and an inhibition of tumor growth. Inhibits Na⁺ channel.
Peptide sequence
N/A
CAS number
170632-47-0
Molecular weight
304.34
Category
Biochemicals
Other name
3-(5'-Hydroxymethyl-2'-furyl)-1-benzylindazole
Molecular formula
C₁₉H₁₆N₂O₂
Physical appearance
White to pale yellow solid
Supplied with
N/A
Is this a salt?
N/A
Is it cell-permeable?
Yes
Purification
≥98% by NMR
Reconstitute instructions
DMSO (100 mM) or EtOH (50 mM)
Storage condition
-20°C
Shipping condition
gel pack
Maximum time for storage
24 months
Storage instructions
Protect from air and light
Tissue
cell
Additional description
For cells, cell lines and tissues in culture till half confluency.