Amidepsine A, Humcola sp. for cell activation

Catalog number
2147-500
Name
Amidepsine A, Humcola sp. for cell activation
Size
500 µg
Price
284.00 EUR
Supplier

Details

Description
A diacylglycerol acyltransferase (DGAT) inhibitor. Shows inhibitory effect in rat liver microsomes (IC₅₀ = 10.2 µM) and Raji cells (IC₅₀ = 15.5 µM). Excessive accumulation of triacetylglycerol produced by DGAT may cause fatty liver, obesity and hypertriglyceridemia, which may lead to atherosclerosis, diabetes and metabolic disorders.
Peptide sequence
N/A
CAS number
169181-28-6
Molecular weight
567.55
Category
Biochemicals
Other name
N-[4-[[4-[(2,4-Dimethoxy-6-methylbenzoyl)oxy]-2-hydroxy-6-methylbenzoyl]oxy]-2-hydroxy-6-methylbenzoyl]-L-alanine
Molecular formula
C₂₉H₂₉NO₁₁
Physical appearance
Off-white solid
Supplied with
N/A
Is this a salt?
No
Is it cell-permeable?
Yes
Purification
≥95% by HPLC
Reconstitute instructions
DMSO or EtOH
Storage condition
-20°C
Shipping condition
gel pack
Maximum time for storage
24months
Storage instructions
Protect from air and light
Tissue
cell
Additional description
For cells, cell lines and tissues in culture till half confluency.