Amidepsine D, Humcola sp. for cell activation

Catalog number
2148-500
Name
Amidepsine D, Humcola sp. for cell activation
Size
500 µg
Price
284.00 EUR
Supplier

Details

Description
An inhibitor of diacylglycerol acyltransferase (DGAT). Shows inhibitory effect in rat liver microsomes (IC₅₀ = 17.5 µM) and Raji cells (IC₅₀ = 2.8µM). Excessive accumulation of triacetylglycerol produced by DGAT may cause fatty liver, obesity and hypertriglyceridemia, which may lead to atherosclerosis, diabetes and metabolic disorders.
Peptide sequence
N/A
CAS number
79786-34-8
Molecular weight
496.48
Category
Biochemicals
Other name
N-[4-[[4-[(2,4-Dimethoxy-6-methylbenzoyl)oxy]-2-hydroxy-6-methylbenzoyl]oxy]-2-hydroxy-6-methylbenzoic acid
Molecular formula
C₂₆H₂₄NO₁₀
Physical appearance
Slighly pinkish white solid
Supplied with
N/A
Is this a salt?
No
Is it cell-permeable?
Yes
Purification
≥95% by HPLC
Reconstitute instructions
DMSO or EtOH
Storage condition
-20°C
Shipping condition
gel pack
Maximum time for storage
24months
Storage instructions
Protect from air and light
Tissue
cell
Additional description
For cells, cell lines and tissues in culture till half confluency.