AS601245 for cell activation

Catalog number
2162-1
Name
AS601245 for cell activation
Size
1 mg
Price
159.00 EUR
Supplier

Details

Description
Cell-permeable. AS601245 is a potent, ATP-competitive JNK inhibitor (hJNK1: IC₅₀ = 150 nM, hJNK2: IC₅₀ = 220 nM and hJNK3: IC₅₀ = 70 nM). Displays anti-inflammatory properties and has been shown to reduce TNF-α plasma levels induced by LPS in mice.
Peptide sequence
N/A
CAS number
345987-15-7
Molecular weight
372.45
Category
Biochemicals
Other name
(Z)-2-(Benzo[d]thiazol-2(3H)-ylidene)-2-(2-((-(pyridine-3-yl)ethyl)amino)pyridine-4-yl)acetonitrile
Molecular formula
C₂₀H₁₆N₆S
Physical appearance
White to yellow solid
Supplied with
N/A
Is this a salt?
No
Is it cell-permeable?
Yes
Purification
≥95% by HPLC
Reconstitute instructions
DMSO (10 mg/ml)
Storage condition
-20°C
Shipping condition
gel pack
Maximum time for storage
24months
Storage instructions
Protect from light and mositure
Tissue
cell
Additional description
For cells, cell lines and tissues in culture till half confluency.