Pluripotin for cell activation

Catalog number
2165-5
Name
Pluripotin for cell activation
Size
5 mg
Price
664.00 EUR
Supplier

Details

Description
Pluripotin (SC1) regulates mouse embryonic stem cell (ESC) self-renewal. It was shown that SC1 is sufficient for sustaining long-term self-renewal of mouse ES cells in an undifferentiated state in the absence of LIF, feeder cells, or serum. SC1 acts through dual inhibition of Ras-GAP and ERK1 with Kd values of 98 and 212 nM, respectively.
Peptide sequence
N/A
CAS number
839707-37-8
Molecular weight
550.54
Category
Biochemicals
Other name
N-​(3-​(7-​(1,​3-​dimethyl-​1H-​pyrazol-​5-​ylamino)-​1-​methyl-​2-​oxo- ​1,​2-​dihydropyrimido[4,​5-​d]pyrimidin-​3(4H)-​yl)-​4-​methylphenyl)-​ 3-​(trifluoromethyl)benzamide; SC1
Molecular formula
C₂₇H₂₅F₃N₈O₂
Physical appearance
White solid
Supplied with
N/A
Is this a salt?
No
Is it cell-permeable?
Yes
Purification
≥97% by HPLC
Reconstitute instructions
DMSO (100 mM)
Storage condition
-20°C
Shipping condition
gel pack
Maximum time for storage
24months
Storage instructions
Protect from air and light
Tissue
cell
Additional description
For cells, cell lines and tissues in culture till half confluency.