Heptelidic Acid for cell activation
Catalog number
2215-1000
Name
Heptelidic Acid for cell activation
Size
1 mg
Price
480.00 EUR
Supplier
Details
Description
A sesquiterpene antibiotic, isolated from Trichoderma sp. A potent and selective glyceraldehyde 3-phosphate dehydrogenase (GAPDH) inhibitor. Binds to the essential Cys149 residue in the catalytic site of GAPDH. Selectively kills high-glycolytic cancer cells through glucose-dependent active ATP deprivation. Selective and competitive inhibitor of mammalian DNA polymerases beta, lambda and terminal deoxynucleotidyl transferase (TdT) in family X of pols.
Peptide sequence
N/A
CAS number
74310-84-2
Molecular weight
280.32
Category
Biochemicals
Other name
Koningic acid; Avocettin; FO-4443; BRN 5091359
Molecular formula
C₁₅H₂₀O₅
Physical appearance
White solid
Supplied with
N/A
Is this a salt?
No
Is it cell-permeable?
Yes
Purification
³95% by HPLC
Reconstitute instructions
DMSO or EtOH
Storage condition
-20°C
Shipping condition
gel pack
Maximum time for storage
24months
Storage instructions
Protect from air and light
Tissue
cell
Additional description
For cells, cell lines and tissues in culture till half confluency.
