DMOG for cell activation

Catalog number
2216-25
Name
DMOG for cell activation
Size
25 mg
Price
295.00 EUR
Supplier

Details

Description
A cell-permeable prolyl 4-hydroxylase (P4H) inhibitor; inhibits hypoxia-inducible factor α (HIF-α) prolyl hydroxylase (HIF-PH). Increases levels of HIF-1α; promotes cell survival under hypoxic conditions. DMOG posseses neuroprotective effect on NFG deprived cell cultures through preservation of glucose metabolism. DMOG also attenuates myocardial injury in a rabbit ischemia reperfusion model.
Peptide sequence
N/A
CAS number
89464-63-1
Molecular weight
175.14
Category
Biochemicals
Other name
N-(2-Methoxy-2-oxoacetyl)glycine methyl ester
Molecular formula
C₆H₉NO₅
Physical appearance
White solid
Supplied with
N/A
Is this a salt?
No
Is it cell-permeable?
Yes
Purification
³98% by NMR
Reconstitute instructions
DMSO (100 mM) or H₂O (100 mM)
Storage condition
-20°C
Shipping condition
gel pack
Maximum time for storage
24months
Storage instructions
Protect from light and moisture
Tissue
cell
Additional description
For cells, cell lines and tissues in culture till half confluency.