IPI-145 for cell activation

Catalog number
2445-25
Name
IPI-145 for cell activation
Size
25 mg
Price
567.00 EUR
Supplier

Details

Description
PI-145 is a potent inhibitor of phosphoinositide-3-kinase (PI3K)-d and PI3K-γ isoforms with potential immunomodulating and antineoplastic activities. IPI-145 prevents the activation of the PI3Kd/γ-mediated signaling pathways which may lead to a reduction in cellular proliferation in PI3Kd/γ-expressing tumor cells.
Peptide sequence
N/A
CAS number
1201438-56-3
Molecular weight
416.86
Category
Biochemicals
Other name
(S)-3-(1-((9H-purin-6-yl)amino)ethyl)-8-chloro-2-phenylisoquinolin-1(2H)-one
Molecular formula
C₂₂H₁₇ClN₆O
Physical appearance
White solid
Supplied with
N/A
Is this a salt?
No
Is it cell-permeable?
Yes
Purification
≥98% by HPLC
Reconstitute instructions
DMSO
Storage condition
-20°C
Shipping condition
gel pack
Maximum time for storage
24 months
Storage instructions
Protect from air and light
Tissue
cell
Additional description
For cells, cell lines and tissues in culture till half confluency.