Human CellExp™ CD28, Human recombinant

CD28

T-cell-specific surface glycoprotein CD28 is also known as TP44, is a single-pass type I membrane protein which contains one Ig-like V-type (immunoglobulin-like) domain. is one of the molecules expressed on T cells that provide co-stimulatory signals, which are required for T cell activation. CD28 is the receptor for CD80 (B7.1) and CD86 (B7.2). When activated by Toll-like receptor ligands, the CD80 expression is upregulated in antigen presenting cells (APCs). The CD86 expression on antigen presenting cells is constitutive. CD28 is the only B7 receptor constitutively expressed on naive T cells.

N/A

This protein is fused with a Fc tag at C-terminus and has a calculated MW of 41.8 kDa.

CD28, Tp44

CD28, Tp44

940

CD28

Human

AAH93698

Yes

HEK 293 cells

≥92%

SDS-PAGE, N/A

< 1 EU/μg

Measured by its binding ability in a functional ELISA.

Immobilized Human B7-1, His Tag at 20μg/ml, can bind Human CD28, Fc Tag with a linear of 0.2-20 μg/ml and Human B7-2, His Tag at 2μg/ml, can bind Human CD28, Fc Tag with a linear of 0.01-5 μg/ml

N/A

Immobilized Human B7-1, His Tag at 20μg/ml, can bind Human CD28, Fc Tag with a linear of 0.2-20 μg/ml and Human B7-2, His Tag at 2μg/ml, can bind Human CD28, Fc Tag with a linear of 0.01-5 μg/ml

N/A

-20°C

Gel pack

Lyophilized

Lyophilized

Reconstitute in sterile PBS, pH 7.4 to a concentration of 50 μg/ml

N/A

Centrifuge the vial prior to opening.

For Research Use Only! Not to be used in humans

Human proteins, cDNA and human recombinants are used in human reactive ELISA kits and to produce anti-human mono and polyclonal antibodies. Modern humans (Homo sapiens, primarily ssp. Homo sapiens sapiens). Depending on the epitopes used human ELISA kits can be cross reactive to many other species. Mainly analyzed are human serum, plasma, urine, saliva, human cell culture supernatants and biological samples.

Recombinants or rec. proteins

recombinants