Human CellExp™ BCMA / TNFRSF17, human recombinant

Catalog number
P1074-50
Name
Human CellExp™ BCMA / TNFRSF17, human recombinant
Size
50 µg
Price
529.00 EUR
Supplier

Details

Target
CD269
Background
Tumor necrosis factor receptor superfamily member 17 (TNFRSF17) is also known as B-cell maturation protein (BCMA), CD antigen CD269, which is a member of the TNF-receptor superfamily. TNFRSF17 contains one TNFR-Cys repeat. TNFRSF17 is expressed in mature B-cells, but not in T-cells or monocytes. TNFRSF17 is receptor for TNFSF13B/BLyS/BAFF and TNFSF13/APRIL. TNFRSF17 promotes B-cell survival and plays a role in the regulation of humoral immunity. TNFRSF17 can activate NF-kappa-B and JNK.
Concentration
N/A
Molecular weight
7.5 kDa
Synonym
TNFRSF17, CD269, BCM, BCMA
Other name
TNFRSF17, CD269, BCM, BCMA
NCBI gene number
608
NCBI gene
TNR17
Gene source
Human
NCBI number
Q02223
Recombinant
Yes
Source
HEK 293 cells
Purification
≥90%
Tested applications
SDS-PAGE, N/A
Level of endotoxin
< 1 EU/μg
Tested activity
Measured by its binding ability in a functional ELISA.
Biological activity
Immobilized Human BCMA, His Tag at 5 μg/mL (100 μL/well) can bind Biotinylated Human BAFF with a linear range of 0.24-3.9 ng/mL.
Reesults
N/A
Binding ability
Immobilized Human BCMA, His Tag at 5 μg/mL (100 μL/well) can bind Biotinylated Human BAFF with a linear range of 0.24-3.9 ng/mL.
Unit
N/A
Storage condition
-20°C
Shipping under
Gel pack
Physical appearance
Lyophilized
Physical properties
Lyophilized from 0.22 μm filtered solution in PBS, pH7.4. Generally Mannitol or Trehalose is added as a protectant before lyophilization.
How to reconstitute
Reconstitute in sterile deionized water to a concentration of 50 μg/ml.
Aa sequence
N/A
Before use
Centrifuge the vial prior to opening.
Notes
For Research Use Only! Not to be used in humans
Properties
Human proteins, cDNA and human recombinants are used in human reactive ELISA kits and to produce anti-human mono and polyclonal antibodies. Modern humans (Homo sapiens, primarily ssp. Homo sapiens sapiens). Depending on the epitopes used human ELISA kits can be cross reactive to many other species. Mainly analyzed are human serum, plasma, urine, saliva, human cell culture supernatants and biological samples.
Additional source
Recombinants or rec. proteins
Group
recombinants