Ingenol 3-angelate for cell activation

Catalog number
2593-1
Name
Ingenol 3-angelate for cell activation
Size
1 mg
Price
251.00 EUR
Supplier

Details

Description
Ingenol 3-angelate is a specific Protein Kinase C (PKC) activator and anti-cancer agent.  Displays potent antileukemic activity mediated via the d isoform of PKC.
Peptide sequence
N/A
CAS number
75567-37-2
Molecular weight
430.53
Category
Biochemicals
Other name
(2Z)-2-Methyl-2-butenoic acid (1aR,2S,5R,5aS,6S,8aS,9R,10aR)-1a,2,5,5a,6,9,10,10a-octahydro-5,5a-dihydroxy-4-(hydroxymethyl)-1,1,7,9-tetramethyl-11-oxo-1H-2,8a-methanocyclopenta[a]cyclopropa[e]cyclodecen-6-yl ester; PEP 005; Ingenol mebutate
Molecular formula
C₂₅H₃₄O₆
Physical appearance
White solid
Supplied with
N/A
Is this a salt?
No
Is it cell-permeable?
Yes
Purification
≥98% by HPLC
Reconstitute instructions
DMSO (~ 1 mg/ml) or ETOH
Storage condition
-20°C
Shipping condition
Gel pack
Maximum time for storage
36 months
Storage instructions
Protect from light and air
Tissue
cell
Additional description
For cells, cell lines and tissues in culture till half confluency.