MK-571 for cell activation

Catalog number
2691-5
Name
MK-571 for cell activation
Size
5 mg
Price
175.00 EUR
Supplier

Details

Description
MK-571 is a selective, CysLT1 receptor antagonist. It blocks the binding of leukotriene LTD4, but not LTC4, to human and guinea pig lung membranes with Ki values of 0.22 nM and 2.1 nM, respectively. MK 571 effectively blocks LTD4 activation of recombinant human and murine CysLT1 receptors but is ineffective at blocking LTC4 or LTD4activation of the recombinant human or murine CysLT2 receptors. MK-57 also acts as a specific inhibitor of multi-drug resistance protein-1 (MRP1).
Peptide sequence
N/A
CAS number
115104-28-4
Molecular weight
515.09
Category
Biochemicals
Other name
(E)-​3-​[[[3-​[2-​(7-​chloro-​2-​quinolinyl)ethenyl]phenyl][[3-​(dimethylamino)-​3-​oxopropyl]thio]methyl]thio]-​propanoic acid; L-660,711
Molecular formula
C₂₆H₂₇ClN₂O₃S₂
Physical appearance
Yellow solid
Supplied with
N/A
Is this a salt?
No
Is it cell-permeable?
Yes
Purification
≥95%
Reconstitute instructions
DMSO (~40 mg/ml)
Storage condition
-20°C
Shipping condition
Gel pack
Maximum time for storage
36 months
Storage instructions
Protect from air and light
Tissue
cell
Additional description
For cells, cell lines and tissues in culture till half confluency.