IM-12 for cell activation

Catalog number
2822-5
Name
IM-12 for cell activation
Size
5 mg
Price
142.00 EUR
Supplier

Details

Description
IM-12 is a potent and selective GSK-3β inhibitor (IC₅₀ = 53 nM). It significantly increases β-catenin levels, leads to TCF-induction and promotes neuronal differentiation in human neural progenitor cells via activation of canonical Wnt signaling.
Peptide sequence
N/A
CAS number
1129669-05-1
Molecular weight
377.41
Category
Biochemicals
Other name
3-(4-Fluorophenylethylamino)-1-methyl-4-(2-methyl-1H-indol-3-yl)-1H-pyrrole-2,5-dione
Molecular formula
C₂₂H₂₀FN₃O₂
Physical appearance
Yellow orange solid
Supplied with
N/A
Is this a salt?
No
Is it cell-permeable?
yes
Purification
≥98% by HPLC
Reconstitute instructions
DMSO (25 mg/ml) or EtOH (5 mg/ml)
Storage condition
-20°C
Shipping condition
Gel Pack
Maximum time for storage
36 months
Storage instructions
Protect from air and light
Tissue
cell
Additional description
For cells, cell lines and tissues in culture till half confluency.