TDZD-8 for cell activation

Catalog number
2854-5
Name
TDZD-8 for cell activation
Size
5 mg
Price
142.00 EUR
Supplier

Details

Description
TDZD-8 is a non-ATP competitive inhibitor of the serine/threonine kinase glycogen synthase kinase 3β (GSK3β; IC₅₀ = 2 µM), binding to the active site of GSK3β. It does not significantly affect the activities of Cdk-1/cyclin B, CK-II, cAMP-dependent protein kinase, or protein kinase C (IC₅₀s = >100 µM). TDZD-8 also causes rapid death of leukemia stem and progenitor cells.
Peptide sequence
N/A
CAS number
327036-89-5
Molecular weight
222.26
Category
Biochemicals
Other name
4-Benzyl-2-methyl-1,2,4-thiadiazolidine-3,5-dione
Molecular formula
C₁₀H₁₀N₂O₂S
Physical appearance
White solid
Supplied with
N/A
Is this a salt?
No
Is it cell-permeable?
Yes
Purification
≥98% by HPLC
Reconstitute instructions
DMSO (>10 mg/ml)
Storage condition
-20°C
Shipping condition
gel pack
Maximum time for storage
36 months
Storage instructions
Protect from air and light
Tissue
cell
Additional description
For cells, cell lines and tissues in culture till half confluency.