BAY 41-2272 for cell activation

Catalog number
9429-5
Name
BAY 41-2272 for cell activation
Size
5 mg
Price
186.00 EUR
Supplier

Details

Description
BAY 41-2272 is a soluble guanylyl cyclase (sGC) activator; acts at a nitric oxide (NO)-independent regulatory site in the sGC α1 subunit. Inhibits platelet aggregation (IC₅₀ = 36 nM) and phenylephrine-induced contractions of rabbit aorta (IC₅₀ = 0.30 μM). Also reduces vascular smooth muscle growth through cAMP- and cGMP-dependent PKA and PKG pathways.
Peptide sequence
N/A
CAS number
256376-24-6
Molecular weight
360.39
Category
Biochemicals
Other name
5-Cyclopropyl-2-[1-[(2-fluorophenyl)methyl]-1H-pyrazolo[3,4-b]pyridin-3-yl]-4-pyrimidinamine
Molecular formula
C₂₀H₁₇FN₆
Physical appearance
White solid
Supplied with
N/A
Is this a salt?
No
Is it cell-permeable?
Yes
Purification
≥98%
Reconstitute instructions
DMSO (>35 mg/ml)
Storage condition
-20°C
Shipping condition
gel pack
Maximum time for storage
36 months
Storage instructions
Protect from air and light
Tissue
cell
Additional description
For cells, cell lines and tissues in culture till half confluency.