MK-4827 for cell activation
Catalog number
9462-25
Name
MK-4827 for cell activation
Size
25 mg
Price
1023.00 EUR
Supplier
Details
Description
MK-4827 is a potent and selective PARP-1 and PARP-2 inhibitor with IC₅₀ values of 3.8 nM and 2.1 nM, respectively. It induces synthetic lethality in preclinical tumour models with loss of BRCA and PTEN function.
Peptide sequence
N/A
CAS number
1038915-60-4
Molecular weight
320.39
Category
Biochemicals
Other name
2-[4-[(3S)-piperidin-3-yl]phenyl]indazole-7-carboxamide; Niraparib
Molecular formula
C₁₉H₂₀N₄O
Physical appearance
Light yellow solid
Supplied with
N/A
Is this a salt?
N/A
Is it cell-permeable?
Yes
Purification
≥98% by HPLC
Reconstitute instructions
DMSO (>4 mg/ml)
Storage condition
-20°C
Shipping condition
Gel pack
Maximum time for storage
36 months
Storage instructions
Protect from air and light
Tissue
cell
Additional description
For cells, cell lines and tissues in culture till half confluency.
