MN64 for cell activation
Catalog number
B1127-10
Name
MN64 for cell activation
Size
10 mg
Price
186.00 EUR
Supplier
Details
Description
MN64 is a potent and selective tankyrase (TNKS) inhibitor (IC₅₀ values of 6 and 72 nM for TNKS1 and TNKS2 respectively). It has no effect on PARP-1 or PARP-2 (IC₅₀ > 19 µM). Through its effects on TNKS, MN-64 inhibits signaling along the Wnt/β-catenin pathway in a cell-based reporter assay.
Peptide sequence
N/A
CAS number
92831-11-3
Molecular weight
264.32
Category
Biochemicals
Other name
2-[4-(1-methylethyl)phenyl]-4H-1-benzopyran-4-one
Molecular formula
C₁₈H₁₆O₂
Physical appearance
Pale yellow solid
Supplied with
N/A
Is this a salt?
No
Is it cell-permeable?
Yes
Purification
≥98% by HPLC
Reconstitute instructions
DMSO (>20 mg/ml) or EtOH (>20 mg/ml)
Storage condition
-20°C
Shipping condition
gel pack
Maximum time for storage
36 months
Storage instructions
Protect from air and light
Tissue
cell
Additional description
For cells, cell lines and tissues in culture till half confluency.
