AG-120 (Ivosidenib) for cell activation

Catalog number
B1163-25
Name
AG-120 (Ivosidenib) for cell activation
Size
25 mg
Price
414.00 EUR
Supplier

Details

Description
AG-120 is a potent isocitrate dehydrogenase type 1 (IDH1) inhibitor, with potential antineoplastic activity. Upon oral administration it specifically inhibits a mutated form of IDH1 in the cytoplasm inhibiting the formation of oncometabolite, 2-hydroxyglutarate (2HG). This leads to induction of cellular differentiation and an inhibition of cellular proliferation
Peptide sequence
N/A
CAS number
1448346-63-1
Molecular weight
582.97
Category
Biochemicals
Other name
(2S)-N-(1-(2-chlorophenyl)-2-((3,3-difluorocyclobutyl)amino)-2-oxoethyl)-1-(4-cyanopyridin-2-yl)-N-(5-fluoropyridin-3-yl)-5-oxopyrrolidine-2-carboxamide
Molecular formula
C₂₈H₂₂ClF₃N₆O₆
Physical appearance
White Solid
Supplied with
N/A
Is this a salt?
No
Is it cell-permeable?
Yes
Purification
≥98% by HPLC
Reconstitute instructions
DMSO (>5 mg/ml))
Storage condition
-20°C
Shipping condition
gel pack
Maximum time for storage
36 months
Storage instructions
Protect from air and light
Tissue
cell
Additional description
For cells, cell lines and tissues in culture till half confluency.