Bardoxolone for cell activation

Catalog number
B1170-5
Name
Bardoxolone for cell activation
Size
5 mg
Price
186.00 EUR
Supplier

Details

Description
Bardoxolone is a synthetic oleanane triterpenoid that inhibits cellular iNOS production when stimulated by IFNg, TNF-α and IL-1. It is Reata’s investigational lead molecule for CKD (chronic kidney disease). It is a potent inducer of the transcription factor Nrf2 which is an important biological target that controls the production of many of the body’s antioxidant and detoxification enzymes.
Peptide sequence
N/A
CAS number
218600-44-3
Molecular weight
491.66
Category
Biochemicals
Other name
2-cyano-3,12-dioxo-oleana-1,9(11)-dien-28-oic acid; RTA 402; CDDO
Molecular formula
C₃₁H₄₁NO₄
Physical appearance
Light brown Solid
Supplied with
N/A
Is this a salt?
No
Is it cell-permeable?
Yes
Purification
≥98% by HPLC
Reconstitute instructions
DMSO (>4.5 mg/ml)
Storage condition
-20°C
Shipping condition
gel pack
Maximum time for storage
36 months
Storage instructions
Protect from air and light
Tissue
cell
Additional description
For cells, cell lines and tissues in culture till half confluency.