SR9009 for cell activation

Catalog number
B1210-50
Name
SR9009 for cell activation
Size
50 mg
Price
567.00 EUR
Supplier

Details

Description
SR9009 is a REV-ERB agonist that increases the constitutive repression of genes regulated by REV-ERB α (IC50=670 nM) and REV-ERBβ (IC50 = 800 nM). SR9009 decreases the circadian locomotor activity during dark phase through activation of REV-ERB, altering the expression pattern of core clock genes in the hypothalamai of mice. In in vivo experiments SR9009 has shown to decrease body fat and improved dyslipidemia and hyperglycemia.
Peptide sequence
N/A
CAS number
1379686-30-2
Molecular weight
437.94
Category
Biochemicals
Other name
 Ethyl 3-[[[(4-chlorophenyl)methyl][(5-nitro-2-thienyl)methyl]amino]methyl]-1-pyrrolidinecarboxylate
Molecular formula
C₂₀H₂₄ClN₃O₄S
Physical appearance
Off White solid
Supplied with
N/A
Is this a salt?
No
Is it cell-permeable?
Yes
Purification
≥98% by HPLC
Reconstitute instructions
DMSO(>40 mg/ml)
Storage condition
-20°C
Shipping condition
gel pack
Maximum time for storage
36 months
Storage instructions
Protect from air and light
Tissue
cell
Additional description
For cells, cell lines and tissues in culture till half confluency.