Indoleamine 2,3-Dioxygenase 1 (IDO1) Inhibitor Screening Kit

Catalog number
K976-100
Name
Indoleamine 2,3-Dioxygenase 1 (IDO1) Inhibitor Screening Kit
Size
100 assays
Price
745.00 EUR
Supplier

Details

Storage Conditions
-20°C
Tag Line
Highly Sensitive; Includes recombinant IDO1 enzyme as positive control.
Shipping Conditions
gel pack
Shelf life
12 months
Species Reactivity
Mammalian
Applications
Rapid, high-throughput screening of drugs and novel ligands.Development of structure-activity relationship (SAR) models to predict IDO1 inhibition liability of novel compounds.
Sample Type
Samples containing drugs, inhibitors or ligands (compounds that can interact and affect IDO1 activity)
Description
Tissue, pathway, proteinase, peptidase, protease ,acrosin, lipoprotein, activator, caspase, trypsin, papain, esterase inhibitors are proteins or receptor ligands or receptor antagonists that bind to an enzyme receptor and decreases its activity. Since blocking an enzyme's activity can kill a pathogen or correct a metabolic imbalance, many drugs are enzyme inhibitors. Not all receptor antagonist that bind to enzymes are inhibitors; enzyme activator ligands or agonists bind to enzymes and increase their enzymatic activity, while enzyme substrates bind and are converted to products in the normal catalytic cycle of the enzyme.