Target Alternative Name
IGF2, IGF-2, IGF 2, insln like growth factor-2, insln like growth factor 2
E. coli expressed human IGF-II
100 µg (0.5 mg/ml) antigen affinity purified rabbit anti-human IGF-II polyclonal antibody in phosphate buffered saline (PBS), pH 7.2, containing 30% glycerol, 0.5% BSA, and 0.01% thimerosal.
Western blot, Neutralization
For Research Use Only! Not to be used in humans.
The antibody solution should be gently mixed before use.
If you buy Antibodies supplied by Biovision they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
IGF-I, IGF-II, insulin-like growth factors -1 and -2 are important regulators of signaling that mediates growth and metabolism in cells. Insulin-like growth factor -1 shares structural homology with proinsulin and is mainly produced by liver. IGF-1 acts via specific receptor, IGF-1R, a heterodimeric tyrosine kinase receptor that signals to various second messenger pathways such as MAPK, Raf/Ras and PI3K cascades.